The focus of this role will involve work on the development and running of assays suitable for the screening of chemotherapeutic agents against Wolbachia bacterial endosymbionts of filarial nematodes. (Ref 007)
The Department of Parasitology at LSTM is one of the largest of its kind with a broad portfolio of research activities targeted at improving the control of parasitic diseases worldwide. We have an exciting opportunity for a Post-Doctoral Research Assistant (PDRA) to support the A·WOL consortium which is a drug discovery and development programme to develop safe macrofilaricides for river blindness and elephantiasis.
The focus of this role will involve work on the development and running of assays suitable for the screening of chemotherapeutic agents against Wolbachia bacterial endosymbionts of filarial nematodes. Screening will be based on assays using in vitro cell/tissue/parasite culture and in vivo models of Brugia malayi and Onchocerca sp. with parasitological, bio-imaging and qPCR endpoint analysis.
The successful candidate will need to have a PhD in biomedical research, preferably with experience of filarial parasite life-cycles and/or in vivo drug screening. It is essential that you have experience of in vitro cell/tissue/parasite culture with in vivo experimentation and drug screening using parasite animal models. We are looking for an individual with excellent communication skills (both written and verbal), well developed research and analytical skills, plus the ability to work as an integral and co-operative member of a multi-disciplinary research team.
The Liverpool School of Tropical Medicine (LSTM) is an internationally recognised centre of excellence for research in tropical diseases. Through the creation of effective links with governments, organisations and institutions and by responding to the health needs of communities, LSTM aims to promote improved health, particularly for people of the less developed/resource poorest countries in the tropics and sub-tropics.
If you are interested in applying, please return your up to date CV and covering letter (quoting reference 007) stating your interest and suitability for the role, together with completed copies of our Application Form, Personal Details Form and Equal Opportunities Monitoring Form, via email to firstname.lastname@example.org, or by post to HR, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA
Closing Date: Monday 8 February 2016, 12.00pm UK Time