André Bastos Daher

PhD Student

Prior to the current activities in LSTM, Andre Daher was the head of the clinical research division of Farmanguinhos/Fiocruz, a Federal governmental pharmaceutical industry in Rio de Janeiro, Brazil. He also used to coordinate two collaborative initiatives in clinical research at Fiocruz Vice Presidency of Research: The Clinical Research Platform for Technological Development in Public Health, and the Fiocruz Clinical Research Network.

He is a medical doctor specialized in Infectious Diseases by the Fluminense Federal University and in Clinical Research by the Oswaldo Cruz German Hospital/Brazilian Ministry of Health. Over the course of his career, he has gained expertise on technological development in pharmaceuticals and served as consultant for international networks. He is currently a consultant for clinical trials in malaria at the Brazilian Ministry of Health and a Scientific Advisory Committee member of the Drugs for Neglected Disease initiative.

Current Research

1. New approaches to treat malaria vivax in Brazil. The evaluation of Artemisin-based Combination Therapies associated to primaquine during seven days to treat uncomplicated malaria vivax in Brazil is an innovative approach. Nevertheless, it is aligned to renowned infectious disease treatments’ trends: the use of multiple drugs in combination, a single treatment to all malaria species, and a patient friendly regimen.

2. Evaluation of P.vivax relapse rates in Brazil. The evaluation of the vivax epidemiology may shed light in the efficiency of the P.vivax radical treatment in Brazil (primaquine during seven days) and drive future field interventions or guidelines updates.

 PhD supervisors: Professor David Lalloo, and Professor Feiko ter Kuile

Selected publications

  • André Daher Júlio C. A. L. Silva, Antony Stevens, Paola Marchesini, C. J. Fontes, F. O. Ter Kuile and David G. Lalloo Evaluation of Plasmodium vivax malaria recurrence in Brazil Malaria Journal 2019 18:18 

    MILLIGAN, RACHAEL; DAHER, ANDRE; GRAVES, PATRICIA M. Primaquine at alternative dosing schedules for preventing relapse in people with Plasmodium vivax malaria. Cochrane Database of Systematic Reviews 2017, Issue 5. Art. No.: CD012656.

    PEREIRA, DHELIO; DAHER, ANDRÉ; ZANINI, GRAZIELA; MAIA, IVAN; FONSECA, LAIS; PITTA, LUCIANA; RUFFATO, ROSILENE; MARCHESINI, PAOLA; FONTES, COR JESUS Safety, efficacy and pharmacokinetic evaluations of a new coated chloroquine tablet in a single-arm open-label non-comparative trial in Brazil: a step towards a user-friendly malaria vivax treatment. MALARIA JOURNAL. (2015): 3,0790, v.15, 2016

    DAHER, ANDRÉ; HERMOSO, M. C. Evaluation of the Federal Senate Proposal to Create the First Brazilian Law in Clinical Research: A Fiocruz Assessment. (Avaliação da proposta do senado para a primeira lei brasileira sobre pesquisa clínica: uma perspectiva da Fiocruz) In: Filosofia, Saúde e Bioética no Instituto Oswaldo Cruz: novos desafios do século XXI. 1 ed. Porto Alegre: Editora Fi, 2016, p. 46.