Dr Lee Haines

Post Doctoral Researcher

Credit Randall Munroe. xkcd comic

 

Things of interest

1) Incredible footage of a tsetse fly giving birth thanks to the perseverance and photographic skill of colleague Geoffrey Attardo at Yale University. 

2) "The Winged Death" by the infamous cosmic horror fiction writer,  H. P. Lovecraft. 

3) Take care of your micro biome! 

4) Entertaining and enlightening blog by the journal Parasites and Vectors called Bugbitten: 

Research

A. Plated bacterial symbionts

B. Tsetse fly feeding through a silicone membrane (photo credit: Ray Wilson

C. Trypanosomes expressing green fluorescent protein within an excised tsetse salivary gland (photo credit: Urvashi Ramphul)

D. Lesson on the physiology of tsetse pupae  (photo credit: Lauren Knerual)

E. National Insect Week 2014 at the World Museum (photo credit: Deirdre Walshe)

F. Seeking Art within Science

Memberships

  • British Society of Parasitology
  • Royal Entomological Society
  • American Society for Biochemistry and Molecular Biology
  • British Society for Protist Biology
  • Infectious Disease Research Network
  • National Trust

Public Engagement

23th March 2018       Radio Merseyside "SciFri. You can listen to the podcast here.

15 March 2018          Microbes to Mosquitoes workshop at Centre 63 

15 September 2017  Radio Merseyside "SciFri" . You can listen to the podcast here.

26 November 2016.  Artist Teachers Association SciArt Intervention project 

12 February 2016     Zika virus symposium: Facts, research questions and knowledge gaps

21 April 2016            Zika virus: Separating Fact from Fiction at Kirkby SciBar

6 September 2016   “Zika fever: truths and half-truths” at Knutsford SciBar

23 Jun 2016             Zika virus: Separating Fact from Fiction at Wilmslow SciBar

Publications

  • Selected Publications

    Spotlight on leishmaniasis in India and the Middle East Microbiology Today February 2017 Lee Haines & Geraldine Foster 

    Genome sequence of the tsetse fly (Glossina morsitans): vector of African trypanosomiasis.  International Glossina Genome Initiative. 2014. Science. 344(6182):380-6.

    Rose, C., Belmonte, R., Armstrong, SD, Molyneux, G., Haines, L., Lehane, M., Wastling, J and Acosta-Serrano, A.  2014.  An investigation into the protein composition of the teneral Glossina morsitans morsitans peritrophic matrix. PLoS Neglected Tropical Diseases. 8(4):e2691.

    Haines, LR. 2013. Examining the tsetse teneral phenomenon and permissiveness to trypanosome infection. Frontiers in Cellular and Infection Microbiology 19(3): 84.

    Walshe, DP, Lehane, MJ and Haines, LR. 2011.  Post eclosion age predicts the prevalence of midgut trypanosome infections in Glossina. PLoS One 6(11): e26984.

    Alves-Silva J, Ribeiro JM, Van Den Abbeele J, Attardo G, Hao Z, Haines LR, Soares MB, Berriman M, Aksoy S, Lehane MJ.  2010.  An insight into the sialome of Glossina morsitans morsitans.  BMC Genomics 11: 213.

    Haines, LR, Lehane, SM, Pearson, TW and Lehane, MJ 2010.  Tsetse EP protein protects the fly midgut from trypanosome establishment.  PLoS Pathogens 6:e1000793.

    Haines, LR, Jackson, AM, Thomas, JM, Watson, CN, Gowen, B, Hancock, RW and Pearson, TW.  2009. Killing of parasites by a structurally modified bovine host defense peptide.  PLoS Neglected Tropical Diseases 3: e373.

    Walshe, DP, Lehane, S, Lehane, MJ and Haines, LR 2009.  Prolonged gene knockdown in the tsetse fly Glossina by feeding double stranded RNA. Insect Molecular Biology 18:11-19.

    Walshe, D. P., Ooi, C.P. Lehane, M.J. and Haines, L.R. 2009.  The enemy within: interactions between tsetse, trypanosomes and symbionts.  Advances in Insect Physiology 37:119-175.

    Hu C, Rio RV, Medlock J, Haines LR, Nayduch D, Savage AF, Guz N, Attardo GM, Pearson TW, Galvani AP, Aksoy S.  2008.  Infections with immunogenic trypanosomes reduce tsetse reproductive fitness: potential impact of different parasite strains on vector population structure.  PLoS Neglected Diseases 12:e192.

    Hu C(1), Rio RV, Medlock J, Haines LR, Nayduch D, Savage AF, Guz N, Attardo GM, Pearson TW, Galvani AP, Aksoy S. Infections with immunogenic trypanosomes reduce tsetse reproductive fitness: potential impact of different parasite strains on vector population structure. PLoS Negl Trop Dis. 2008 Mar 12;2(3):e192. doi: 10.1371/journal.pntd.0000192.

    Eamon P. Breen, Sebastien G. Gouin,Andrew F. Murphy,Lee R. Haines,Angela M. Jackson,Terry W. Pearson,Paul V. Murphy and Richard K. Porter. On the Mechanism of Mitochondrial Uncoupling Protein 1 Function. January 27, 2006 The Journal of Biological Chemistry 281, 2114-2119.

    Carroll AM(1), Haines LR, Pearson TW, Fallon PG, Walsh CM, Brennan CM, Breen EP, Porter RK. Identification of a functioning mitochondrial uncoupling protein 1 in thymus.J Biol Chem. 2005 Apr 22;280(16):15534-43. Epub 2005 Jan 28.

    Chase JC(1), Dawson-Coates JA, Haddow JD, Stewart MH, Haines LR, Whitaker DJ, Ken ML, Olafson RW, Pearson TW.Analysis of Kudoa thyrsites (Myxozoa: Myxosporea) spore antigens using monoclonal antibodies. Dis Aquat Organ. 2001 Jun 20;45(2):121-9.