Dr Hayley Tyrer

Post Doctoral Research Assistant

Areas of Interest

In vivo drug screening, in vivo models of disease, lymphatic filariasis

Background

Hayley Tyrer graduated from the University of York in 2008 with a BSc (Hons) in Biology (with a year in Europe). Shortly after graduating she began work as a research assistant in Professor Steve Brown’s group at the Medical Research Council, Mammalian Genetics Unit in Oxfordshire. Here she researched novel therapeutic compounds for the treatment of otitis media (glue ear). Hayley stayed on at the Mammalian Genetics Unit to undertake her PhD; supervised by Dr Michael Cheeseman, Dr Paul Potter and Professor Steve Brown. Her research focus concerned the role of hypoxia inducible factor in chronic models of otitis media. She obtained her PhD in 2013 and was awarded a small project grant to continue some work from her PhD. In October 2013, Hayley joined Professor Mark Taylor’s group in the Filariasis research laboratory as a post-doctoral research assistant as part of the AWOL Consortium.

Teaching

Hayley is a demonstrator on DTM&H, MSc personal tutor and is involved with various course modules.

Professional Memberships & Other Relevant Expertise

  • Member of the British Society of Parasitology
  • Guest blogger for BugBitten, Copyeditor for University of Oxford Phenotype magazine
  • Member of the LSTM STEM Ambassador Team
  • Member of LSTM’s Public Engagement Working Group
  • STEM Ambassador (training complete August 2015)

Publications

  • A murine macrofilaricide screening model for onchocerciasis and lymphatic filariasis. Alice Halliday, Ana F Guimaraes, Hayley E Tyrer, Heally Metuge, Chounna Patrick, Kengne-Ouafo Arnoud, Tayong Kwenti, George Forsbrook, Andrew Steven, Darren Cook, Peter Enyong, Samuel Wanji, Mark J Taylor and Joseph D Turner. Parasites and Vectors (2014); 7 (472): doi: 10.1186/s13071-014-0472-z.

    What have we learnt from murine models of otitis media? Hayley E. Tyrer, Michael Crompton & Mahmood F. Bhutta. Current Allergy and Asthma Reports (2013); 13(5): 501-511. doi: 10.1007/s11882-013-0360-1.

    A mouse model for osseous heteroplasia. Michael T Cheeseman, Kate Vowell, Tertius A. Hough, Lynn Jones, Paras Phatak, Hayley E. Tyrer, Michelle Kelly, Roger Cox, Madhuri V. Warren & Jo Peters. PLoS One (2012); 7(12): e51835. doi: 10.1371/journal.pone.0051835.

    HIF-VEGF Pathways are Critical for Chronic Otitis Media in Junbo and Jeff mouse mutants. Michael T Cheeseman, Hayley E Tyrer, Debbie Williams, Tertius A Hough, Paras Pathak, Maria R Romero, Helen Hilton, Sulzhan Bali, Andrew Parker, Lucie Vizor, Tom Purnell, Kate Vowell, Sara Wells, Mahmood F Bhutta, Paul K Potter & Steve DM Brown. PLoS Genetics (2011); 7(10): e1002336. doi 10.1371/journal.pgen.1002336.