Dr Tony Nolan

Senior Lecturer

1997 BSc at Imperial College: Applied Biology
2003 PhD at Imperial College: A transformation technology for mosquito vectors of malaria
2003-2008 Postdocs at University of Rome “la Sapienza” and University College London looking at genome defence mechanisms against genetic parasites and ageing.
2008-2018 Senior Research Fellow in the Target Malaria research consortium, leading research to develop gene drives for the control of the malarial mosquito.

Selected publications

  • Kyrou K, Hammond AM, Galizi R, Kranjc N, Burt A, Beaghton AK, Nolan T and Crisanti A A CRISPR-Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes Nature Biotechnology 2018, 36, pages1062–1066

    A Hammond, K Kyrou, M Bruttini, A North, R Galizi, X Karlsson, F Carpi, R D’Aurizio, A Crisanti and T Nolan The dynamics of creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito PLoS Genetics 2017, Oct 9

    A Hammond, R Galizi, K Kyrou, A Simoni, C Siniscalchi, D Katsanos, M Gribble, D Baker, E Marois, S Russell, A Burt, N Windbichler, A Crisanti and T Nolan. A CRISPR-based Gene Drive System Targeting Female Reproduction in the Malaria Mosquito. Nature Biotechnology 34,78–83 (2016)