LSTM Seminar Series: Trypanosomes and Leishmania – drug targets in protein kinase gene families

News article 10 Apr 2013
40

The seminar series continued today with a presentation by Professor Jeremy Mottram entitled: Trypanosomes and Leishmania: drug targets in protein kinase gene families.

Jeremy Mottram is Professor of Molecular and Cellular Parasitology at the University of Glasgow as well as deputy director of the Wellcome Centre for Molecular Parasitology at Glasgow University and an internationally renowned researched on haemoflagellate parasites, mainly Leishmania and African trypanosomes. He also sits on the Infections and Immunity board of the MRC.

The seminar, introduced by Dr. Alvaro Acosta Serrano of LSTM’s Parasitology department gave an historical overview of the discovery and analysis of the genomics of the various Leishmania and trypanosomes and the life cycle of the parasites. It reflected on the work of the Mottram Laboratory in Glasgow, especially on its research on the molecular genetics, cell biology and biochemistry of parasitic protozoa that are the causative agents of the neglected tropical diseases leishmaniasis and Human African Trypanosomiasis (HAT).

The primary research goal of the laboratory is to understand the molecular mechanisms by which Leishmania and Trypanosoma brucei parasites undergo cellular remodelling during their complex life cycles.