Workpackage 5: Mathematical modelling of diagnostic algorithms

Workpackage 5 uses the information generated in Workpackage 2, 3 and 4 for the mathematical modelling of diagnostic algorithms. We aim to develop flexible mathematical models for M. tuberculosis detection by specific diagnostic tests. This models will define what is the most efficient test combination for the diagnosis of TB and this information will be used to inform the design of clinical trials to test the novel algorithms.