Daniela is a Professor in Respiratory Infection and Vaccine Immunology and the Head of the Department of Clinical Sciences at LSTM.
Daniela is a global leader in Respiratory Infections and Controlled Human Infection Challenge with experience in bacterial challenge, co-infection studies, mucosal immunity (nose and lungs) and vaccine testing and immune responses. She leads a Programme of work on respiratory infections and accelerated vaccine development with over £20million from various funders including BMGF, MRC, UKRI, NIHR and several industry partners. She leads the unique Experimental Human Pneumococcal Consortium in partnership with over 50 laboratories of worldwide experts on respiratory infection and pneumococcal biology. To date her team has safely challenged over 1800 participants with live bacteria in over 30 clinical studies in their bespoke research clinic at the Accelerator. To find out more about the studies look here.
Her team has played a substantial role in the UK covid-19 pandemic response as a trial site for several covid vaccine studies including the Oxford / Astrazeneca vaccine.
Her research focused mainly on:
- Accelerate development and test novel pneumococcal vaccines using experimental carriage
- Understanding nasal and lung immune responses and correlates of protection against respiratory infection with viruses including SARS-CoV2 and bacteria
- Defining how respiratory virus co-infections (flu, RSV and SARS-CoV2) and host susceptibility (asthma, COPD, aging, smoke) alters responses to pneumococcal infection
Daniela is on the management board of the HIC-VAC consortium and Leads the WorkStream on Human Challenge Plataform to accelerate product development in the UKRI Infection Innovation Consortium (iicon) consortium.
Daniela obtained a PhD in Immunology in 2009 from the University of Sao Paulo (São Paulo, Brazil). From 2001 to 2009 Daniela trained at Butantan Institute (Sao Paulo, Brazil) on development of novel vaccines against respiratory infections using different formulations, new adjuvants and routes of immunization. During her PhD Daniela was awarded the prestigious Robert Austrian Research Award in Pneumococcal Vaccinology to develop novel nasal vaccines (2006). Daniela joined the Liverpool School of Tropical Medicine in 2009 as a postdoctoral scientist and was promoted to Professor and Head of department in 2018.
Selected News and Media Appearance:
https://youtu.be/f0Qlu_hUgeU (Globo Mulheres Fantasticas)